Research: diabetes news
Research and clinical studies that help us better understand diabetes: from genetics and microbiota to new therapies in trial stages.
Weight loss doesn't always prevent type 2 diabetes, new study finds
A German study found that even after maintaining 8% weight loss for 9 years, a group of people at high metabolic risk still saw their blood glucose rise and their insulin secretion fall.
Read more →The 2026 update for cardiologists prioritizes cardiorenal benefit when choosing type 2 diabetes treatment
The latest review reinforces a shift in approach: choosing drugs based on their cardiovascular and kidney benefit, even when glucose control is already acceptable.
Read more →A biochemical blood signature identifies people at higher risk of dying from diabetes
Researchers from the URV, IRB-CatSud and CIBEROBN have identified 9 blood metabolites, common to both type 2 diabetes and insulin resistance, associated with a higher risk of death.
Read more →Obesity combined with low muscle mass triples type 2 diabetes risk, study finds
A study published in Diabetes Care found that people with sarcopenic obesity — a combination of excess body fat and muscle loss — are more than three and a half times more likely to develop type 2 diabetes.
Read more →An AI model predicts hospital hypoglycemia 24 hours in advance
Cedars-Sinai researchers developed an LSTM AI model that, using data from nearly 143,000 hospital admissions, predicts which patients are at risk of hypoglycemia up to 24 hours before it happens.
Read more →Why type 2 diabetes is increasingly understood as an inflammatory disease too
There's growing consensus that, beyond a glucose regulation problem, type 2 diabetes involves chronic low-grade inflammation that feeds back into insulin resistance.
Read more →A study of more than 12,000 sensors backs real-world use of the year-long Eversense 365 CGM
A real-world analysis of more than 12,000 Eversense 365 sensors, presented at the ADA's 2026 Scientific Sessions, showed 93% wear time and good glycemic control both on its own and paired with an automated insulin delivery system.
Read more →Two islet cell transplant trials help people with type 1 diabetes stop using insulin
Two independent clinical trials — Eledon Pharmaceuticals with the University of Chicago, and Vertex Pharmaceuticals' VX-880 — show that transplanting pancreatic islet cells can restore insulin production in people with long-standing type 1 diabetes.
Read more →Gut microbiota, a new clue to understanding type 2 diabetes
Researchers identify a link between microbiota composition and glucose metabolism regulation.
Read more →A low-calorie Mediterranean diet combined with exercise cuts type 2 diabetes risk by 31%
The PREDIMED-Plus clinical trial, involving 4,746 adults with overweight or obesity and metabolic syndrome across more than 100 primary care centers in Spain, found a 31% reduction in type 2 diabetes risk with a low-calorie Mediterranean diet, moderate exercise and ongoing professional support.
Read more →Gene therapy: a clinical trial aims to teach muscles to regulate glucose
Biotech company Kriya Therapeutics introduces insulin and glucokinase genes into skeletal muscle through a single intramuscular injection.
Read more →Both type 1 and type 2 diabetes raise dementia risk, large study finds
A study of more than 283,000 people, published in the journal Neurology, found that type 1 diabetes nearly triples dementia risk and type 2 diabetes doubles it, compared with people without diabetes.
Read more →Stem cells without immunosuppression: Sana Biotechnology starts a phase 1 trial
The biotech company is advancing a stem-cell-derived cell therapy that aims to avoid the use of immunosuppressive drugs.
Read more →Prolonged heat exposure during pregnancy doubles the risk of gestational diabetes
A study by IDIAP Jordi Gol covering more than 150,000 pregnancies in the Barcelona metropolitan area over 12 years found that continuous exposure to high temperatures, including at night, for 30 straight days can double the risk of gestational diabetes.
Read more →A large study links semaglutide to lower kidney and cardiovascular risk
A trial with more than 3,500 participants observed a 24% reduction in a composite of serious kidney events and cardiovascular death.
Read more →A project generates insulin-producing cells from human skin for type 1 diabetes
Research co-funded by the DiabetesCERO Foundation has managed to generate, from human skin, cells increasingly similar to the pancreas's beta cells, capable of producing insulin.
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