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Research: diabetes news

Research and clinical studies that help us better understand diabetes: from genetics and microbiota to new therapies in trial stages.

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Weight loss doesn't always prevent type 2 diabetes, new study finds

A German study found that even after maintaining 8% weight loss for 9 years, a group of people at high metabolic risk still saw their blood glucose rise and their insulin secretion fall.

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The 2026 update for cardiologists prioritizes cardiorenal benefit when choosing type 2 diabetes treatment

The latest review reinforces a shift in approach: choosing drugs based on their cardiovascular and kidney benefit, even when glucose control is already acceptable.

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A biochemical blood signature identifies people at higher risk of dying from diabetes

Researchers from the URV, IRB-CatSud and CIBEROBN have identified 9 blood metabolites, common to both type 2 diabetes and insulin resistance, associated with a higher risk of death.

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An AI model predicts hospital hypoglycemia 24 hours in advance

Cedars-Sinai researchers developed an LSTM AI model that, using data from nearly 143,000 hospital admissions, predicts which patients are at risk of hypoglycemia up to 24 hours before it happens.

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Why type 2 diabetes is increasingly understood as an inflammatory disease too

There's growing consensus that, beyond a glucose regulation problem, type 2 diabetes involves chronic low-grade inflammation that feeds back into insulin resistance.

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Gut microbiota, a new clue to understanding type 2 diabetes

Researchers identify a link between microbiota composition and glucose metabolism regulation.

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A low-calorie Mediterranean diet combined with exercise cuts type 2 diabetes risk by 31%

The PREDIMED-Plus clinical trial, involving 4,746 adults with overweight or obesity and metabolic syndrome across more than 100 primary care centers in Spain, found a 31% reduction in type 2 diabetes risk with a low-calorie Mediterranean diet, moderate exercise and ongoing professional support.

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Gene therapy: a clinical trial aims to teach muscles to regulate glucose

Biotech company Kriya Therapeutics introduces insulin and glucokinase genes into skeletal muscle through a single intramuscular injection.

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Stem cells without immunosuppression: Sana Biotechnology starts a phase 1 trial

The biotech company is advancing a stem-cell-derived cell therapy that aims to avoid the use of immunosuppressive drugs.

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A large study links semaglutide to lower kidney and cardiovascular risk

A trial with more than 3,500 participants observed a 24% reduction in a composite of serious kidney events and cardiovascular death.

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A project generates insulin-producing cells from human skin for type 1 diabetes

Research co-funded by the DiabetesCERO Foundation has managed to generate, from human skin, cells increasingly similar to the pancreas's beta cells, capable of producing insulin.

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